Felix Cleemann,Ulrich Hersel,Torben Lessman,Harald Rau
申请号:
US13822170
公开号:
US09133276B2
申请日:
2011.09.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising an exendin linker conjugate D-L1, wherein D represents an exendin moiety; and -L1 is represented by formula (I),wherein the dashed line indicates the attachment to one of the amino groups of the exendin moiety by forming an amide bond. The invention further relates to pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by exendin.