RAU HARALD,CLEEMANN FELIX,HERSEL ULRICH,KADEN-VAGT SILVIA,LESSMANN TORBEN,WEGGE THOMAS
申请号：
NZ59802110
公开号：
NZ598021A
申请日:
2010.07.30
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed herein is a prodrug or a pharmaceutically acceptable salt thereof comprising an insulin linker conjugate D-L, wherein D represents the insulin moiety； and -L is a non-biologically active linker moiety -L1 represented by formula (I), wherein the dashed line indicates the attachment to one of the amino groups of the insulin by forming an amide bond. Additionally disclosed are pharmaceutical compositions comprising said prodrugs as well as their use as a medicament for treating or preventing diseases or disorders which can be treated by insulin.
