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In-situ cross-linkable polymeric compositions and methods thereof
专利权人:
Suneris Inc.
发明人:
Landolina, Joseph A.
申请号:
AU2012334982
公开号:
AU2012334982A1
申请日:
2012.11.12
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
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