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NOUVEAU DERIVE DE COUMARINE AYANT UNE ACTIVITE ANTITUMORALE
专利权人:
CHUGAI SEIYAKU KABUSHIKI KAISHA;SAKAI, TOSHIYUKI
发明人:
申请号:
EP07714330.3
公开号:
EP1982982B1
申请日:
2007.02.09
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y 1 and Y 2 are selected from -N= etc., Y 3 and Y 4 are selected from -CH= etc., A is selected from sulfamide etc., R 1 is selected from hydrogen etc., and R 2 is selected from C 1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
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