The present invention is directed to an amide derivative having excellent BCR-ABL tyrosine kinase inhibitory activity, or a salt thereof.The present invention provides an amide derivative represented by the following general formula [1]:(wherein R1 represents -CH2-R11, etc.； R2 represents alkyl, halogen, haloalkyl, etc.； R3 represents hydrogen, etc.； Het1 represents a group of the formula [6] as above, etc.； and Het2 represents pyrimidinyl, etc.), or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient.The compound of the present invention is useful as a BCR-ABL tyrosine kinase inhibitor.
