FIELD: biotechnology.SUBSTANCE: present invention provides a composition for the detection of an autoantibody targeting VEGFR1, containing an effective amount of the following three antigenic polypeptides: H-DEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLE-OH; H-DLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSI-OH; H-ESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAEL-OH, where the ratio of the individual antigenic polypeptides in the composition is 1:1:1. Also, the present invention provides a method for detecting an immune marker in the blood plasma of an autoantibody targeting VEGFR1 using the VEGFR1 antigen polypeptide described herein and a test kit containing an antigenic VEGFR1 polypeptide.EFFECT: invention expands the arsenal of means of detection autoantibody targeting VEGFR1.5 cl, 1 dwg, 1 tbl
