Nowy proces granulowania i otrzymany w ten sposób granulat

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专利权人:

Egis Gyógyszergyár Zrt.

发明人:

TÖLGYESI, ZOLTÁN,ZSIGMOND, ZSOLT,ÚJFALUSSY, GYÖRGY,LEVENTISZNÉ HUSZÁR, MAGDOLNA,TONKA-NAGY, PÉTER,AGYAGOS, MÓNIKA

申请号：

PL10715338

公开号：

PL2459175T3

申请日:

2010.02.24

申请国别(地区):

PL

年份:

2018

代理人:

摘要：

The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved； b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.

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中国工程科技知识中心

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http://www.ckcest.cn/home/