NEW GRANULATING PROCESS AND THUS PREPARED GRANULATE

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专利权人:

发明人:

申请号：

EP10715338.9

公开号：

EP2459175A2

申请日:

2010.02.24

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.

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