Anticorps anti-CD4 humanisé doté de propriétés immunosuppressives

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专利权人:

Biotest AG

发明人:

申请号：

EP10179921.1

公开号：

EP2332991A3

申请日:

2004.03.19

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Provided is a humanized anti-CD4 antibody which is capable of activating CD4+ CD25+ regulatory T cells, wherein the humanized anti-CD4 antibody comprises a sequence comprising the complementarity-determining regions (CDRs) of the mouse monoclonal anti-CD4 antibody B-F5, optionally with variations in the sequence that do not substantially affect the antibody specificity and/or affinity thereof.

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