#$%^&*AU2016213839A120160901.pdf#####ABSTRACT Disclosed herein is an implant comprising extant BMP-2 bound to demineralized bone, wherein the extant BMP-2 and demineralized bone are each derived from a single cadaver or live donor.3/11 START 302 Harvest cancellous bone and cortical bone from donor 1 304 Grind harvested bone and substantially homogenous mixture of cortical and cancellous bone 306 Expose harvested bone mixture to acetic acid lysing agent 308 Rinse the harvested bone mixture with a rinsing agent 310 Substantially neutralize the pH of the harvested bone mixture 312 Dehydrate the harvested bone mixture C END FIG. 3