Refrida a Crystalline form of dipropilcarbamoilmetilo Ester acid 3 - (3 - [2 - [(e) - 3.5 - diamino - 6 - Chloro - carbonilimino] pyrazine - 2 - - - - 1,3,8 triaza spiro [4.5] Dean - 8 - carbonyl} - c) - propionic bencenosulfonilamino form comprising an x-ray diffraction pattern with two Theta values (+ \/ - 0.2) 7,0\ufffd, 10,6\ufffd, 14,3\ufffd, 18,2\ufffd, 18,6\ufffd, 19,2\ufffd, 21,2\ufffd, 21,8\ufffd, 24,7\ufffd, 29,0\ufffd and 31,5\ufffd at a temperature of between 21\ufffdc and 26\ufffdc Said compu. This activity has on the epithelial sodium channel (ENAC)REFRIDA A UNA FORMA CRISTALINA DEL ESTER DIPROPILCARBAMOILMETILO DEL ACIDO 3-(3-{2-[(E)-3,5-DIAMINO-6-CLORO-PIRAZINA-2-CARBONILIMINO]-1,3,8-TRIAZA-ESPIRO[4.5]DECANO-8-CARBONIL}-BENCENOSULFONILAMINO)-PROPIONICO DE FORMA C QUE COMPRENDE UN PATRON DE DIFRACCION DE RAYOS X CON VALORES 2-THETA (+/-0,2) DE 7,0�, 10,6�, 14,3�, 18,2�, 18,6�, 19,2�, 21,2�, 21,8�, 24,7�, 29,0� Y 31,5� A UNA TEMPERATURA DE ENTRE 21�C Y 26�C. DICHO COMPUESTO TIENE ACTIVIDAD SOBRE LOS CANALES DE SODIO EPITELIAL (ENaC)
