A compression device includes at least one pressurizable bladder tosubstantially occludeblood flow into skin capillary beds adjacent to the at least one pressurizablebladder, and aplurality of perfusion sensors. In operation a first-angiosome sensor detectsthe perfusionparameter of a skin capillary bed in a first angiosome of the limb, and asecond-angiosomesensor detects the perfusion parameter of a skin capillary bed in a secondangiosome of the limbthat is different from the first angiosome. A control circuit maps sensorsignals from the first-angiosomesensor to the first angiosome or a first artery of the limb, and maps sensorsignalsfrom the second-angiosome sensor to the second angiosome or a second artery ofthe limbdifferent from the first artery of the limb. For each perfusion sensor, thecontrol circuitdetermines whether the received sensor signals are indicative of peripheralartery disease.
