The present invention provides a kind of medical composition, it includes PD-1 inhibitor and Hsp90 inhibitor or its tautomer or pharmaceutically acceptable salt, wherein the Hsp90 inhibitor be 3- (2,4- dihydroxy -5- isopropyl-phenyls) -4- (1- Methvl-indole -5- bases) -5- hydroxyls-[1,2,4] triazole or biphosphate 5- hydroxyls -4- (5- hydroxyls -4- (1- Methyl-1H-indole -5- bases) -4H-1,2,4- triazole -3- bases) -2- cumene base esters. The present invention also provides a kind of methods of cancer that individual in need is treated using medical composition as described herein.
