HIGH DRUG LOAD TABLET FORMULATION OF [(1R), 2S]-2-AMINOPROPIONIC ACID 2-[4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO[2,1-f][1,2,4]TRIAZIN-6-YLOXY]-1-METHYLETHYL ESTER
Ajit S. Narang,Sherif Ibrahim Farag Badawy,Ganeshkumar A. Subramanian,Keirnan Ryan LaMarche,Dilbir S. Bindra,Venkatramana M. Rao
申请号：
US13979174
公开号：
US20130296325A1
申请日:
2012.01.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to a high drug load tablet formulation of [(1R),2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester, and to methods of using the formulation in the treatment of cancer. The tablet is obtained by means of a wet granulation process.
