The present invention provides a novel compound having a highly selective [alpha]4 integration inhibiting effect which is low on [alpha]4[beta]1 but high on [alpha]4[beta]7. The present invention provides a sulfonamide derivative with a specific chemical structure or its pharmaceutically acceptable salts, in which the specific chemical structure contains a sulfonamide group at terminal end and the sulfonamide group has a heterocyclic group comprising hetero-atoms or a phenyl group as a substituent group.