substituted phenylsulfones and method of reducing the levels of "alpha" tnf.

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专利权人:

发明人:

HON-WAH MAN,GEORGE MULLER

申请号：

BR9915201

公开号：

BR9915201B1

申请日:

1999.10.19

申请国别(地区):

BR

年份:

2012

代理人:

摘要：

Optical isomer or racemic mixture of phenethylsulfones substituted alpha to the phenyl group with a 1-oxoisoindoline or 1,3-dioxoisoindoline for use in the treatment of an inflammatory, infectious, immunological or malignant disease. A typical embodiment is 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione.

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