FERNANDEZ MEDARDE, ANTONIO,CANEDO HERNANDEZ, LIBRADA MARIA,VINUESA-NAVARRO, MARIA DE LOS ANGELES,SANCHEZ LOPEZ, JOSE MARIA,CALVO PELAZ, BELINDA,MARTINEZ INSUA, MARTA,RODRIGUEZ QUESADA, ANA,GARCIA CABA
申请号:
CA2917744
公开号:
CA2917744A1
申请日:
2014.07.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.