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Oxazolidinone compounds and methods of use thereof as antibacterial agents
专利权人:
Merck Sharp &; Dohme Corp.
发明人:
Jing Su,Lihu Yang,Takao Suzuki
申请号:
US16490958
公开号:
US10752621B2
申请日:
2018.03.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to oxazolidinone Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
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