Mihir B. MANDAL;David B. OLSEN;Jing SU;Takao SUZUKI;Lanying YOU;Lihu YANG;Merck Sharp & Dohme Corp.;Katherine YOUNG
发明人:
Mihir B. Mandal,David B. Olsen,Jing Su,Lihu Yang,Katherine Young,Takao Suzuki,Lanying You
申请号：
US15766395
公开号：
US20180290987A1
申请日:
2016.10.17
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
