GALLEY, GUIDO,GROEBKE ZBINDEN, KATRIN,NORCROSS, ROGER,STALDER, HENRI
申请号：
CA2676944
公开号：
CA2676944C
申请日:
2008.02.05
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The invention relates to compounds of formula (I) wherein R1 is aryl or heteroaryl, wherein the aryl and heteroaryl groups may be unsubstituted or substituted by one to three substituents, selected from the group consisting of cycloalkyl, phenyl, phenyloxy, benzyl, benzyloxy, halogen, lower alkyl, lower alkoxy, heteroaryl, piperidin-1-yl or by lower alkyl substituted by halogen, or is aryl or heteroaryl wherein at least one hydrogen atom is replaced by deuterium or tritium； R2 is hydrogen, lower alkyl or is benzyl unsubstituted or substituted by alkoxy or halogen； or R1 and R2 form together with the N-atom to which they are attached 2,3-dihydroindol-1-yl or 3,4-dihydro-quinolin-1-yl； R3 is hydrogen or lower alkyl or to a pharmaceutically suitable acid addition salt thereof for the treatment of CNS disorders.
