The present invention relates to a process for preparing an extract from one or more botanical raw materials, such as Indigo Naturalis and the extract itself. The present invention also relates to a composition comprising the extract, as well as the use of composition in medical or cosmetic applications.本發明提供一種關於自一或多種植物原料,例如中藥青黛及其萃取物製備萃取物之製程。本發明亦關於一種包含該萃取物之組成物,以及組成物在醫藥或化妝品應用之用途。