A process of manufacturing a totally implantable venous device is provided with forming a catheter securing a locking nut of the catheter is secured to a proximal end of the catheter forming a base of injection seat forming a connecting tube to communicate with injection seat and catheter putting the locking nut on a bulged central portion of the connecting tube forming a base and a housing by injection molding with the base of injection seat disposed therein and the locking nut disposed in both the housing and the base forming a space on a top of the injection seat to communicate with the injection seat and forming an injection membrane in the space to seal the space.
