This invention relates to a drug containing edible acid and/or acidic salt as active agent to treat and alleviate hypersensitivity diseases by lowering the humor pH and method; to improve individual hypersensitivity diseases by uses of health care food, which are made from said edible acid and/or acidic salt, or the acidic fruits containing thereof, or their products; foods lowering the risk of hypersensitivity and their preparation methods; drug to lower the humor acidity and to treat or alleviate disease caused by insects bite toxin; that also to be drug for cold or virus infection; drug for inflammation; drug for analgesic; and drug for thrombus disease; method lowers the hypersensitivity risk of clothing or grove and their products.