Yan Sun;Jianhui Yang;Hongbo Zhang;Ting Li;Shunnan Zhang;Xiaolin Bai;Lina Dong
发明人:
Shunnan Zhang,Jianhui Yang,Lina Dong,Hongbo Zhang,Xiaolin Bai,Yan Sun,Ting Li
申请号：
US12306371
公开号：
US08951568B2
申请日:
2007.06.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A pharmaceutical granule whose shape is spherical or sphere-like shape with a bulk density of 0.6-1.3 g/ml and a dissolution time of 0.5-5 minutes, which is prepared as follows: mother granules are filled into a fluidized-bed as bed charge； active pharmaceutical ingredients are prepared into a suspension or solution whose viscosity is adjusted to 6.0-9.8 Mpa·S with viscosity adjusting agent； then it is sprayed onto surface of said mother granule to obtain final granule.
