An aerosol delivery device is provided that includes at least one housing enclosing a reservoir configured to retain an aerosol precursor composition. The device includes a heating element, and a microprocessor configured to operate in an active mode in which the control body is configured to control the heating element to activate and vaporize components of the aerosol precursor composition. And the device includes a heart rate monitor including a plurality of biopotential electrodes affixed to the housing and configured to obtain biopotential measurements from a user, and including signal conditioning circuitry configured to produce an electrocardiogram signal from the biopotential measurements. The microprocessor is coupled to the signal conditioning circuitry and further configured to control operation of at least one functional element of the aerosol delivery device based on the electrocardiogram signal or a heart rate of the user calculated therefrom.