Smart Brain S.r.o.;Ustav Molekularni Genetiky Akademie Ved CR, V.V.I.
发明人:
申请号：
EP18719029.3
公开号：
EP3606534A1
申请日:
2018.03.29
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides 1-acyl-lysophosphatidyl derivatives of general formula I, (I) wherein R is C4 to C30 alifatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, R3 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, or R3 is not present. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.
