Christian Lavedan,Simona Volpi,Louis Licamele,Kendra Tomino Mack,Callie Michelle Heaton
申请号:
US14723965
公开号:
US20150259747A1
申请日:
2015.05.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention describes an association between genetic polymorphisms in the ceramide kinase-like (CERKL) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.