Boehringer Ingelheim International GmbH;Boehringer Ingelheim Pharma GmbH & Co. KG
发明人:
申请号：
EP12180787.9
公开号：
EP2543669A2
申请日:
2007.02.07
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention relates to a specific salt of a dihydropteridione derivative, namely the trihydrochloride salt of the compound N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to its crystallisation in the form of an hydrate with water, to a process for the manufacture thereof, and to the use thereof in a pharmaceutical composition.
