GRAUERT, MATTHIAS,LINZ, GUENTER,SCHMID, ROLF,SIEGER, PETER
申请号:
CA2635834
公开号:
CA2635834C
申请日:
2007.02.07
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to a specific salt of a dihydropteridionederivative, namely the trihydrochloride salt of the compound N-[trans-4-[4-(cyclopropylmethyl)-1- piperazinyl]cyclohexyl]-4-[[(7R)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6- oxo-2-pteridinyl]amino]-3-methoxy-benzamide, to its crystallisation in the form of an hydrate with water, to aprocess for the manufacture thereof, and to the use thereof in apharmaceutical composition.