A controller shifting device for interconnecting an armrest (901) and a controller (902) of a powered wheelchair (900) includes an adjustment mechanism (3). The adjustment mechanism (3) includes a casing (32), a first connection seat (31) connected to the casing (32) for connection with the armrest (901), and a second connection seat (33) connected to the casing (32) for installation of the controller (902). When the casing (32) rotates from an operating position to a folded position, the second connection seat (33) is lowered for placing the controller (902) below the armrest (901).