An oral appliance and accompanying tray is provided, where the oral appliance is fitted to the posterior teeth of the upper jaw and a connecting portion extends between the left and right sides of the mouth, with the connecting portion custom-fitted to contact the palate at or near the palatal nerve to reduce appetite. The present tray has a compressible member configured to closely form the connecting portion to the palatal arch. Further, the tray has flexible ends that are configured to bend up towards the gums and guide the oral appliance to fit the buccal side of the teeth. The tray may include a series of protrusions on the occlusal landing areas to prevent the user from biting through the oral appliance.