ANAN CHUNTHARAPAI,JIN K. KIM,LEONARD G. PRESTA,TIMOTHY STEWART
申请号：
PT02742463
公开号：
PT1362105E
申请日:
2002.01.29
申请国别(地区):
PT
年份:
2012
代理人:
摘要：
The present invention relates generally to the generation and characterization of neutralizing anti-IFN-± monoclonal antibodies with broad reactivity against various IFN-± subtypes. The invention further relates to the use of such anti-IFN-± antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-±, in particular, autoimmune disorders such as insulin-dependant diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
