用於製備包含阿米福丁與胺基酸之腎保護劑的組成物及方法农业专利-农业学术服务平台

发明人:: DELPASSAND, EBRAHIM S.,戴帕圣德　伊伯拉辛Ｓ,戴帕聖德　伊伯拉辛Ｓ,TWOROWSKA, IZABELA,托洛斯卡　伊莎贝拉,托洛斯卡　伊莎貝拉,THAMAKE, SANJAY,瑟马基　桑杰,瑟馬基　桑傑,RANGANATHAN, DAVID,雷贾纳森　大卫,雷賈納森　大衛,戴帕圣德伊伯拉辛S,戴帕聖德伊伯拉辛S,托洛斯卡伊莎贝拉,托洛斯卡伊莎貝拉,瑟马基桑杰,瑟馬基桑傑,雷贾纳森大卫,雷賈納森大衛

摘要：: This invention relates to composition and method of preparation of AminoMedixTM comprising of Amifostine, at least one amino acid (Arginine, Lysine, Histidine) with or without other pharmaceutically active compounds. The AminoMedixTM composition can be applied for kidney protection during therapy using radiolabeled and non-radiolabeled compounds, contrast agents, chemotherapeutics, antibiotics and drugs showing nephrotoxic effect.本發明係相關於一種AminoMedixTM組成物與其製備方法，該組成物包含阿米福丁(Amifostine)、至少一胺基酸(精胺酸、離胺酸、組胺酸)，具有或不具其他醫藥活性化合物。該AminoMedixTM組成物可應用於在使用經放射線標記及/或非放射線標記之化合物、顯影劑、化療、抗生素與顯示腎毒性之藥物進行治療期間，產生腎保護作用。