HOVLAND RAGNAR,SKJAERET TORE,HOLMEIDE ANNE KRISTIN,BRAENDVANG MORTEN
申请号：
ZA201303962
公开号：
ZA201303962B
申请日:
2013.05.30
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
The present disclosure relates to lipid compounds of the general formula (I): R1-O&mdash；C(R2)(R3)-X&emsp；&emsp；(I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds； R2 and R3 are the same or different and may be chosen from different substituents； and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide； or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
