HOVLAND, RAGNAR,HOLMEIDE, ANNE KRISTIN,SKJARET, TORE,BRANDVANG, MORTEN
申请号：
PH12015500930
公开号：
PH12015500930A1
申请日:
2015.04.24
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The present disclosure relates to lipid compounds of the general formula (I): R1-O-C(R2)(R3) -X (I) wherein R1 is a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, or a C10-C22 alkynyl group having 1-6 triple bonds R2 and R3 are the same or different and may be chosen from different substituents and X is a carboxylic acid or a derivative thereof, such as a carboxylic ester, a carboxylic anhydride, a phospholipid, triglyceride, or a carboxamide or a pharmaceutically acceptable salt, solvate, solvate of such salt or a prodrug thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising at least one compound according to the present disclosure, and to such compounds for use as medicaments or for use in therapy, in particular for the treatment of diseases related to the cardiovascular, metabolic, and inflammatory disease area.
