Disclosed in the present invention are an application of 5[alpha]-androst-3[beta],5,6[beta]-triol and an analogue, a deuterated substitute, or a pharmaceutically acceptable salt thereof in the preparation of a drug for the treatment of haemorrhagic stroke. The haemorrhagic stroke is a brain parenchymal haemorrhage, a subarachnoid haemorrhage, or both.本發明揭示了5α-雄甾-3β,5,6β-三醇及其類似物、氘代物或其醫藥學上可接受之鹽在製備治療患者之出血性腦中風之藥物中之應用。該出血性腦中風係腦實質出血、蛛網膜下腔出血或二者併發。