Recombinant RNA-Dependent RNA Polymerase of RNA Viruses

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专利权人:

The Governors of the University of Alberta

发明人:

Matthias Götte,Egor Petrovitch Tchesnokov

申请号：

US16646916

公开号：

US20200277648A1

申请日:

2018.09.04

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present disclosure provides nucleic acids, expression vectors, host cells for producing recombinant viral RNA-dependent RNA polymerase (RdRp) polypeptides of viruses such as Ebola virus. The present disclosure also provides methods and substrates for assaying activity of a RdRp polypeptide or a RdRp complex. Also provided herein are inhibitors of RdRp polypeptides of viruses such as Ebola virus for use in treating or preventing viral infection.

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中国工程科技知识中心

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