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NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE
专利权人:
The United States of America; as represented by the Secretary; Department of Health and Human Servic
发明人:
Mark Connors,Jinghe Huang,Byong Ha Kang,John Mascola,Elise Ishida,Tongqing Zhou,Peter Kwong,Anqi Zheng
申请号:
US16786267
公开号:
US20200231658A1
申请日:
2020.02.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
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