The United States of America; as repsented By the Secretary; Department of Health and Human Services
发明人:
Mark Connors,Jinghe Huang,Byong Ha Kang,John Mascola,Elise Ishida,Tongqing Zhou,Peter Kwong,Anqi Zheng
申请号:
US15559791
公开号:
US20180298083A1
申请日:
2016.03.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Antibodies and antigen binding fragments that specifically bind to gp120 and neutralize HIV-1 are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.