Dana Farber Cancer Institute, Inc.;The Broad Institute;The General Hospital Corporation d/b/a Massachusetts General Hospital;President and Fellows of Harvard College
发明人:
申请号：
EP19164054.9
公开号：
EP3536323A1
申请日:
2015.08.08
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present disclosure provides methods of treating and/or preventing inflammatory bowel disease (IBD) and graft-versus-host disease (GVHD) using salt-inducible kinase (SIK) inhibitors, such as macrocyclic SIK inhibitors of Formula (I), imidazolyl SIK inhibitors of Formula (II), and urea and carbamate SIK inhibitors of Formula (III-A) (e.g., urea and carbamate SIK inhibitors of Formula (III)).
