Ugur Sahin,Ozlem Tureci,Michael Koslowski,Rita Mitnacht-Kraus
申请号：
US14977325
公开号：
US10596256B2
申请日:
2015.12.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, hepatocellular cancer, colon cancer, pancreatic cancer, esophageal cancer, head &； neck cancer, kidney cancer, in particular renal cell carcinoma, prostate cancer, liver cancer, melanoma, sarcoma, myeloma, neuroblastoma, placental choriocarcinoma, cervical cancer, and thyroid cancer, and the metastatic forms thereof. In one embodiment, the tumor disease is metastatic cancer in the lung.
