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用於因子XA 抑制劑的解毒劑和其使用方法
专利权人:
发明人:
申请号:
HK17107164.6
公开号:
HK1236989A
申请日:
2017.07.17
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
The present invention relates antidotes to anticoagulants targeting factor Xa. The antidotes are factor X and factor Xa protein derivatives that bind to the factor Xa inhibitors thereby substantially neutralizing them but do not assemble into the prothrombinase complex. The derivatives describe herein lack or have reduced intrinsic coagulant activity. Disclosed herein are methods of reversing anticoagulation, stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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