Method of analysis of effective matter in of oral medicament sort with controlled unlocked of contained polymer or copolymer of derivation of acrylic acid or of methacrylic acid
The present invention relates to a method of making analysis, particularly determination of active substance content and purity thereof in oral controlled-release medicamentous form containing polymer or copolymer of acrylic or methacrylic acid derivatives and a pharmaceutically active polar compound being selected from the group consisting of tamsulosin hydrochloride and venlafaxine hydrochloride, using standard analytic methods such as HPLC, characterized by transferring the active compound into a solution using dimethylsulfoxide, optionally a dimethylsulfoxide- containing solvent mixture.The present invention relates to a method of making analysis, particularly determination of active substance content and purity thereof in oral controlled-release medicamentous form containing polymer or copolymer of acrylic or methacrylic acid derivatives and a pharmaceutically active polar compound being selected from the group consisting of tamsulosin hydrochloride and venlafaxine hydrochloride, using standard analytic methods such as HPLC, characterized by transferring the active compound into a solution using dimethylsulfoxide, optionally a dimethylsulfoxide- containing solvent mixture.
