The Board of Trustees of the Leland Stanford Junior University
发明人:
Roeland Nusse,Karl H. Willert
申请号：
US15637903
公开号：
US10066206B2
申请日:
2017.06.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
