Mark Godfrey Jenkins;Paul Anthony McCarron;Ryan Gerald Loughlin
发明人:
Paul Anthony McCarron,Mark Godfrey Jenkins,Ryan Gerald Loughlin
申请号：
US12733776
公开号：
US09272038B2
申请日:
2008.09.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A gel formulation for use in filling a wound cavity and delivering active ingredient thereto, having a pH range of 6.5 to 7.5, low bioadhesive strength and cohesive integrity and being a PVA borate gel including an active ingredient and a modulator to bind borate and/or PVA in aqueous solution through a mono-diol or di-diol formation and reduces the pH of PVA-borate hydrogels. A suitable modulator is a sugar alcohol such as mannitol and the active ingredient, a medicament suitable for topical application such as a local anaesthetic and/or an antibiotic.
