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method for preparing a tablet, and calcium carbonate tablet
专利权人:
NYCOMED PHARMA AS
发明人:
HENRIK RAVN AAGE,PEDER MOHR OLSEN,POUL EGON BERTELSEN,THOMAS THISTED
申请号:
BRPI0921599
公开号:
BRPI0921599A2
申请日:
2009.11.17
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to a method for the preparation of a tablet comprising at least 50% w/w of calcium carbonate, the method comprising i) providing a particulate composition comprising a) calcium carbonate, b) a binding sugar alcohol selected from sorbitol or isomalt, or combinations thereof, c) a non-binding sugar alcohol selected from mannitol, maltitol or xylitol, or combinations thereof, and ii) compressing said composition using a tabletting machine equipped with at least one pair of punches and dies, wherein the pair of punches and die before filling the die with said particulate composition is sprayed with a composition comprising a lubricant selected from magnesium stearate, calcium stearate or stearic acid or combinations thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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