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Devoid of Imidazole as CCR2 Receptor Antagonists
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
JOHANNES AEBI,ALFRED BINGGELI,LUKE GREEN,GUIDO HARTMANN,HANS P. MAERKI,PATRIZIO MATTEI,FABIENNE RICKLIN,OLIVIER ROCHE
申请号:
BRPI0814403
公开号:
BRPI0814403A2
申请日:
2008.06.23
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention is concerned with novel imidazole derivatives of formula (I), wherein m, E, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.
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