Macdonald, Lynn,Murphy, Andrew,Mcwhirter, John,Gurer, Cagan,Harris, Faith,Stevens, Sean,Voronina, Vera
申请号:
NZ71937312
公开号:
NZ719373A
申请日:
2012.10.26
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
Disclosed is a chimeric human/non-human animal MHC I polypeptide, wherein a human portion of the chimeric polypeptide comprises α1, α2, and α3 domains of a human HLA class I polypeptide and a non-human portion of the chimeric polypeptide comprises transmembrane and cytoplasmic domains of a non-human animal MHC I polypeptide. Further discloses are nucleic acids encoding said polypeptide.