THE PRESENT INVENTION PROVIDES A MULTIVALENT IMMUNOGENIC COMPOSITION HAVING 15 DISTINCT. POLYSACCHARIDE - PROTEIN CONJUGATES. EACH CONJUGATE CONSISTS OF A CAPSULAR POLYSACCHARIDE PREPARED FROM A DIFFERENT SEROTYPE OF STREPTOCOCCUS PNEUMONIAE (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F OR 33F) CONJUGATED TO A CARRIER PROTEIN, PREFERABLY CRM197. THE IMMUNOGENIC COMPOSITION, PREFERABLY FORMULATED AS A VACCINE ON AN ALUMINUM-BASED ADJUVANT, PROVIDES BROAD COVERAGE AGAINST PNEUMOCOCCAL DISEASE, PARTICULARLY IN INFANTS AND YOUNG CHILDREN.