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SYSTEM AND METHOD FOR QUANTITATIVE MAPPING OF RADIOACTIVITY PRODUCTION RATE DURING PROTON THERAPY
专利权人:
The General Hospital Corporation
发明人:
Georges El Fakhri,Nathaniel Alpert,Xuping Zhu,Kira Grogg
申请号:
US15095827
公开号:
US20160296766A1
申请日:
2016.04.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides a system and method for method for quantifying radioactivity production during a proton treatment of a patient. In some aspects, a method includes administering, using a proton delivery system, a proton treatment using at least one therapeutic proton beam generating positron emitting radionuclides within a region of interest (ROI) of a patient, and acquiring, using an emission tomography system, emission tomography data indicative of an activity of the positron emitting radionuclides in the ROI. The method also includes quantifying, based on a kinetic model, a radioactivity production rate of at least one positron emitting radionuclide using the emission tomography data. The method further includes generating at least one map indicative of the radioactivity production rate of the at least one positron emitting radionuclide.
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